Post-exposure prophylaxis of rabies infection after exposure to scratches, bites or other injuries caused by a suspected rabid animal; mucous membrane contamination w/ infectious tissue or saliva of a suspected rabid animal; contact of mucous membranes or newly skin injury w/ rabies live attenuated vaccine eg, vaccination baits.
Rarely, allergic reactions including BP fall, dyspnoea, cutaneous reactions; generalized reactions eg, chills, fever, headache, malaise, nausea, vomiting, arthralgia & moderate back pain; CV reactions if inadvertently injected IV. Local reactions (local pain at the inj site, tenderness or swelling).
May impair the efficacy of live attenuated virus vaccines eg, measles, rubella, mumps & varicella vaccines for a period of up to 3 mth. May result in misleading +ve test results in serological testing due to transitory rise of passively transferred Abs after inj. May interfere w/ some serological tests for red cell allo-Abs (eg, Coombs' test).
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